I've been in real multiple attacks before, what works for me is focusing on the closet opponent and working your way out , concentrating on sweeps, eye strikes, throat strikes, and knee attacks...I want to end this quickly with the least amount of damage to myself first and foremost..at that point in time, you become hypervigilent and your martial arts training plays a major role in your survival...I do not want to kill my opponents, just incapicitate them for the time being...thats where control comes in as well...easier said than done..I know, that's why I train