umm, as with any fight anything is possible. Although in a street fight karate strikes are much more effective. Boxers train to throw heavy punches to inflict damage with a glove on. Karate students are supposed to train to throw accurate breaking punches, elbows, knees, kicks etc. The karate student would also have an advantage because it is possible that he is trained to fight a boxer. While the boxer probably has no training to fight a karate student. The boxer should have the edge on conditioning however if properly trained the karate student should understand economy of motion and not tire as quickly. Any proper street fight shouldnt last more than a minute or so. Rarely will a street fight last as long as a boxing match or probably even a boxing round unless there are multiple participants. There are always passers by, police, bouncers etc... so conditioning in my opinon will be a mute point. Strength is probably going to go to the boxer as they in thier sport have to fight for a very very long time. Boxers are also used to fighting in their weight division so fighting outside of it may throw them off, while a karate student doesnt share the same problem. So a good karate fighter vs a good boxer in a street fight with luck and chaos being out of the equation. The fighter will win as he is trained to fight. A good boxer vs a karate fighter in a boxing ring. The boxer will win as he is trained to box. karate practioner from mcDojo's R us vs boxer in boxing ring or street fight. The boxer will win as he is trained to box and karate practioner is trained in technique but not the use of.